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Structure of transcription coactivator SAGA

Gene transcription by RNA polymerase II is regulated by activator proteins that recruit the coactivator complexes SAGA(1,2) and TFIID(2–4). SAGA is globally required for regulated transcription(5) and conserved amongst eukaryotes(6). SAGA contains four modules(7–9), the activator-binding Tra1 module...

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Detalles Bibliográficos
Autores principales: Wang, Haibo, Dienemann, Christian, Stützer, Alexandra, Urlaub, Henning, Cheung, Alan C.M., Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994259/
https://www.ncbi.nlm.nih.gov/pubmed/31969703
http://dx.doi.org/10.1038/s41586-020-1933-5