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Structure of transcription coactivator SAGA
Gene transcription by RNA polymerase II is regulated by activator proteins that recruit the coactivator complexes SAGA(1,2) and TFIID(2–4). SAGA is globally required for regulated transcription(5) and conserved amongst eukaryotes(6). SAGA contains four modules(7–9), the activator-binding Tra1 module...
Autores principales: | Wang, Haibo, Dienemann, Christian, Stützer, Alexandra, Urlaub, Henning, Cheung, Alan C.M., Cramer, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994259/ https://www.ncbi.nlm.nih.gov/pubmed/31969703 http://dx.doi.org/10.1038/s41586-020-1933-5 |
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