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RNA-binding Motif Protein 10 Induces Apoptosis and Suppresses Proliferation by Activating p53

RNA-binding motif protein 10 (RBM10) is an RNA-binding protein frequently deleted or mutated in lung cancer cells. Recent reports showed that knockdown of RBM10 in human cancer cells enhances growth of mouse tumor xenografts, suggesting that RBM10 acts as a tumor suppressor. RBM10 also regulates alt...

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Detalles Bibliográficos
Autores principales: Jung, Ji Hoon, Lee, Hyemin, Cao, Bo, Liao, Peng, Zeng, Shelya X., Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994357/
https://www.ncbi.nlm.nih.gov/pubmed/31591476
http://dx.doi.org/10.1038/s41388-019-1034-9