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Inhibition of CRY2 by STAT3/miRNA-7-5p Promotes Osteoblast Differentiation through Upregulation of CLOCK/BMAL1/P300 Expression

Accumulating evidence indicates that cryptochrome circadian regulatory (CRY) proteins have emerged as crucial regulators of osteogenic differentiation. However, the associated mechanisms are quite elusive. In this study, we show that knockdown of CRY2 downregulated the expression of runt-related tra...

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Detalles Bibliográficos
Autores principales: Tang, Zhenghui, Xu, Tianyuan, Li, Yinghua, Fei, Wenchao, Yang, Gong, Hong, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994415/
https://www.ncbi.nlm.nih.gov/pubmed/31982773
http://dx.doi.org/10.1016/j.omtn.2019.12.020