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UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase from the snail Biomphalaria glabrata – structural reflections

UDP-GalNAc:polypeptide GalNAc transferase (ppGalNAcT; EC 2.4.1.41) is the initiating enzyme for mucin-type O-glycosylation in animals. Members of this highly conserved glycosyltransferase family catalyse a single glycosidic linkage. They transfer an N-acetylgalactosamine (GalNAc) residue from an act...

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Detalles Bibliográficos
Autores principales: Turupcu, Aysegül, Poliak, Peter, Margreitter, Christian, Oostenbrink, Chris, Staudacher, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994419/
https://www.ncbi.nlm.nih.gov/pubmed/31396754
http://dx.doi.org/10.1007/s10719-019-09886-y