Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G

APOBEC3G, a member of the double-domain cytidine deaminase (CD) APOBEC, binds RNA to package into virions and restrict HIV-1 through deamination-dependent or deamination-independent inhibition. Mainly due to lack of a full-length double-domain APOBEC structure, it is unknown how CD1/CD2 domains conn...

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Detalles Bibliográficos
Autores principales: Yang, Hanjing, Ito, Fumiaki, Wolfe, Aaron D., Li, Shuxing, Mohammadzadeh, Nazanin, Love, Robin P., Yan, Maocai, Zirkle, Brett, Gaba, Amit, Chelico, Linda, Chen, Xiaojiang S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994475/
https://www.ncbi.nlm.nih.gov/pubmed/32005813
http://dx.doi.org/10.1038/s41467-020-14377-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994475/
https://www.ncbi.nlm.nih.gov/pubmed/32005813
http://dx.doi.org/10.1038/s41467-020-14377-y

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