Vaccination with virosomally formulated recombinant CyRPA elicits protective antibodies against Plasmodium falciparum parasites in preclinical in vitro and in vivo models

The Plasmodium falciparum (Pf) cysteine-rich protective antigen (PfCyRPA) has emerged as a promising blood-stage candidate antigen for inclusion into a broadly cross-reactive malaria vaccine. This highly conserved protein among various geographical strains plays a key role in the red blood cell inva...

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Detalles Bibliográficos
Autores principales: Tamborrini, Marco, Hauser, Julia, Schäfer, Anja, Amacker, Mario, Favuzza, Paola, Kyungtak, Kwak, Fleury, Sylvain, Pluschke, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994490/
https://www.ncbi.nlm.nih.gov/pubmed/32025340
http://dx.doi.org/10.1038/s41541-020-0158-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994490/
https://www.ncbi.nlm.nih.gov/pubmed/32025340
http://dx.doi.org/10.1038/s41541-020-0158-9

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