A limited sampling schedule to estimate individual pharmacokinetics of pemetrexed in patients with varying renal functions

PURPOSE: Pemetrexed is a widely used cytostatic agent with an established exposure–response relationship. Although dosing is based on body surface area (BSA), large interindividual variability in pemetrexed plasma concentrations is observed. Therapeutic drug monitoring (TDM) can be a feasible strate...

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Detalles Bibliográficos
Autores principales: de Rouw, Nikki, Visser, Sabine, Koolen, Stijn L. W., Aerts, Joachim G. J. V., van den Heuvel, Michel M., Derijks, Hieronymus J., Burger, David M., ter Heine, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994532/
https://www.ncbi.nlm.nih.gov/pubmed/31853639
http://dx.doi.org/10.1007/s00280-019-04006-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994532/
https://www.ncbi.nlm.nih.gov/pubmed/31853639
http://dx.doi.org/10.1007/s00280-019-04006-x

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