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Sensitive Automated Measurement of Histone-DNA Affinities in Nucleosomes

The DNA of eukaryotes is wrapped around histone octamers to form nucleosomes. Although it is well established that the DNA sequence significantly influences nucleosome formation, its precise contribution has remained controversial, partially owing to the lack of quantitative affinity data. Here, we...

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Detalles Bibliográficos
Autores principales: Schnepf, Max, Ludwig, Claudia, Bandilla, Peter, Ceolin, Stefano, Unnerstall, Ulrich, Jung, Christophe, Gaul, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994541/
https://www.ncbi.nlm.nih.gov/pubmed/31982782
http://dx.doi.org/10.1016/j.isci.2020.100824