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Sensitive Automated Measurement of Histone-DNA Affinities in Nucleosomes
The DNA of eukaryotes is wrapped around histone octamers to form nucleosomes. Although it is well established that the DNA sequence significantly influences nucleosome formation, its precise contribution has remained controversial, partially owing to the lack of quantitative affinity data. Here, we...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994541/ https://www.ncbi.nlm.nih.gov/pubmed/31982782 http://dx.doi.org/10.1016/j.isci.2020.100824 |