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Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells

BACKGROUND: The retinal pigment epithelium (RPE) has the potential to regenerate the entire neuroretina upon retinal injury in amphibians. In contrast, this regenerative capacity has been lost in mammals. The reprogramming of differentiated somatic cells into induced pluripotent stem cells (iPSCs) b...

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Detalles Bibliográficos
Autores principales: Chen, Fenghua, Liu, Xiao, Chen, Yao, Liu, John Y., Lu, Huayi, Wang, Wei, Lu, Xiaoqin, Dean, Kevin C., Gao, Ling, Kaplan, Henry J., Dean, Douglas C., Peng, Xiaoyan, Liu, Yongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994567/
https://www.ncbi.nlm.nih.gov/pubmed/31982829
http://dx.doi.org/10.1016/j.ebiom.2019.102618