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Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling

Neural stem/progenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to brain repair during CNS disease. The microenvironment within the SVZ stem cell niche controls NSPC fate. However, extracellular factors within the niche that trigger astrogliogenesis over neurogenesis d...

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Detalles Bibliográficos
Autores principales: Pous, Lauriane, Deshpande, Sachin S., Nath, Suvra, Mezey, Szilvia, Malik, Subash C., Schildge, Sebastian, Bohrer, Christian, Topp, Könül, Pfeifer, Dietmar, Fernández-Klett, Francisco, Doostkam, Soroush, Galanakis, Dennis K., Taylor, Verdon, Akassoglou, Katerina, Schachtrup, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994610/
https://www.ncbi.nlm.nih.gov/pubmed/32005867
http://dx.doi.org/10.1038/s41467-020-14466-y