Cargando…
Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
Neural stem/progenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to brain repair during CNS disease. The microenvironment within the SVZ stem cell niche controls NSPC fate. However, extracellular factors within the niche that trigger astrogliogenesis over neurogenesis d...
Autores principales: | Pous, Lauriane, Deshpande, Sachin S., Nath, Suvra, Mezey, Szilvia, Malik, Subash C., Schildge, Sebastian, Bohrer, Christian, Topp, Könül, Pfeifer, Dietmar, Fernández-Klett, Francisco, Doostkam, Soroush, Galanakis, Dennis K., Taylor, Verdon, Akassoglou, Katerina, Schachtrup, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994610/ https://www.ncbi.nlm.nih.gov/pubmed/32005867 http://dx.doi.org/10.1038/s41467-020-14466-y |
Ejemplares similares
-
P75 neurotrophin receptor controls subventricular zone neural stem cell migration after stroke
por: Deshpande, Sachin S., et al.
Publicado: (2021) -
Pointing fingers at blood contact: mechanisms of subventricular zone neural stem cell differentiation
por: Malik, Subash C., et al.
Publicado: (2022) -
Fibrinogen triggered signaling pathways modify stem cell behavior in central nervous system disease
por: Lin, Jia-Di, et al.
Publicado: (2020) -
Id proteins: emerging roles in CNS disease and targets for modifying neural stemcell behavior
por: Chu, Yu-Hsuan, et al.
Publicado: (2021) -
Nuclear pore complex remodeling by p75(NTR) cleavage controls TGF-β signaling and astrocyte functions
por: Schachtrup, Christian, et al.
Publicado: (2015)