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Downregulation of testosterone production through luteinizing hormone receptor regulation in male rats exposed to 17α-ethynylestradiol

The pharmaceutical 17α-ethynylestradiol (EE2) is considered as an endocrine-disrupting chemical that interferes with male reproduction and hormonal activation. In this study, we investigated the molecular mechanism underlying EE2-regulatory testosterone release in vitro and in vivo. The results show...

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Detalles Bibliográficos
Autores principales: Lin, Po-Han, Kuo, Tsung-Hsien, Chen, Chih-Chieh, Jian, Cai-Yun, Chen, Chien-Wei, Wang, Kai-Lee, Kuo, Yuh-Chen, Shen, Heng-Yi, Hsia, Shih-Min, Wang, Paulus S., Lieu, Fu-Kong, Wang, Shyi-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994641/
https://www.ncbi.nlm.nih.gov/pubmed/32005928
http://dx.doi.org/10.1038/s41598-020-58125-0