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Downregulation of testosterone production through luteinizing hormone receptor regulation in male rats exposed to 17α-ethynylestradiol
The pharmaceutical 17α-ethynylestradiol (EE2) is considered as an endocrine-disrupting chemical that interferes with male reproduction and hormonal activation. In this study, we investigated the molecular mechanism underlying EE2-regulatory testosterone release in vitro and in vivo. The results show...
Autores principales: | Lin, Po-Han, Kuo, Tsung-Hsien, Chen, Chih-Chieh, Jian, Cai-Yun, Chen, Chien-Wei, Wang, Kai-Lee, Kuo, Yuh-Chen, Shen, Heng-Yi, Hsia, Shih-Min, Wang, Paulus S., Lieu, Fu-Kong, Wang, Shyi-Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994641/ https://www.ncbi.nlm.nih.gov/pubmed/32005928 http://dx.doi.org/10.1038/s41598-020-58125-0 |
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