miR-155 Overexpression in OT-1 CD8(+) T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen

Therapy by adoptive transfer of ex vivo-expanded tumor-infiltrating or genetically modified T cells may lead to impressive clinical responses. However, there is a need to improve in vivo persistence and functionality of the transferred T cells, in particular, to face the highly immunosuppressive env...

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Detalles Bibliográficos
Autores principales: Monnot, Gwennaëlle C., Martinez-Usatorre, Amaia, Lanitis, Evripidis, Lopes, Silvia Ferreira, Cheng, Wan-Chen, Ho, Ping-Chih, Irving, Melita, Coukos, George, Donda, Alena, Romero, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994712/
https://www.ncbi.nlm.nih.gov/pubmed/32021906
http://dx.doi.org/10.1016/j.omto.2019.12.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994712/
https://www.ncbi.nlm.nih.gov/pubmed/32021906
http://dx.doi.org/10.1016/j.omto.2019.12.008

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