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Targeting the IκB Kinase Enhancer and Its Feedback Circuit in Pancreatic Cancer()

Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with an overall median 5-year survival rate of 8%. This poor prognosis is because of the development of resistance to chemotherapy and radiation therapy and lack of effective targeted therapies. IκB kinase enhancer (IKBKE) overexpression wa...

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Detalles Bibliográficos
Autores principales: Challa, Sridevi, Husain, Kazim, Kim, Richard, Coppola, Domenico, Batra, Surinder K., Cheng, Jin Q., Malafa, Mokenge P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994835/
https://www.ncbi.nlm.nih.gov/pubmed/32004866
http://dx.doi.org/10.1016/j.tranon.2019.11.009