Chemokine-Adjuvanted Plasmid DNA Induces Homing of Antigen-Specific and Non–Antigen-Specific B and T Cells to the Intestinal and Genital Mucosae

Plasmid DNA is a promising vaccine platform that together with electroporation can elicit significant systemic Ab responses; however, immunity at mucosal sites remains low. In this study, we sought to program T and B cells to home to the gastrointestinal and vaginal mucosae using genetic chemokine a...

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Detalles Bibliográficos
Autores principales: Aldon, Yoann, Kratochvil, Sven, Shattock, Robin J., McKay, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2020
Materias:
Immunotherapy and Vaccines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994839/
https://www.ncbi.nlm.nih.gov/pubmed/31915263
http://dx.doi.org/10.4049/jimmunol.1901184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994839/
https://www.ncbi.nlm.nih.gov/pubmed/31915263
http://dx.doi.org/10.4049/jimmunol.1901184

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