A human somatic cell culture system for modelling gene silencing by transcriptional interference

Transcriptional interference and transcription through regulatory elements (transcriptional read-through) are implicated in gene silencing and the establishment of DNA methylation. Transcriptional read-through is needed to seed DNA methylation at imprinted genes in the germ line and can lead to aber...

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Detalles Bibliográficos
Autores principales: Kühnel, Theresa, Heinz, Helena Sophie Barbara, Utz, Nadja, Božić, Tanja, Horsthemke, Bernhard, Steenpass, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994850/
https://www.ncbi.nlm.nih.gov/pubmed/32021933
http://dx.doi.org/10.1016/j.heliyon.2020.e03261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994850/
https://www.ncbi.nlm.nih.gov/pubmed/32021933
http://dx.doi.org/10.1016/j.heliyon.2020.e03261

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