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A human somatic cell culture system for modelling gene silencing by transcriptional interference
Transcriptional interference and transcription through regulatory elements (transcriptional read-through) are implicated in gene silencing and the establishment of DNA methylation. Transcriptional read-through is needed to seed DNA methylation at imprinted genes in the germ line and can lead to aber...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994850/ https://www.ncbi.nlm.nih.gov/pubmed/32021933 http://dx.doi.org/10.1016/j.heliyon.2020.e03261 |