Cargando…

Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish

Tgf-β signaling is a major antiproliferative pathway governing different biological functions, including cellular reprogramming. Upon injury, Müller glial cells of zebrafish retina reprogram to form progenitors (MGPCs) essential for regeneration. Here, the significance of Tgf-β signaling for inducin...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Poonam, Gupta, Shivangi, Chaudhary, Mansi, Mitra, Soumitra, Chawla, Bindia, Khursheed, Mohammad Anwar, Saran, Navnoor Kaur, Ramachandran, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994856/
https://www.ncbi.nlm.nih.gov/pubmed/32004993
http://dx.doi.org/10.1016/j.isci.2019.100817