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Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish
Tgf-β signaling is a major antiproliferative pathway governing different biological functions, including cellular reprogramming. Upon injury, Müller glial cells of zebrafish retina reprogram to form progenitors (MGPCs) essential for regeneration. Here, the significance of Tgf-β signaling for inducin...
Autores principales: | Sharma, Poonam, Gupta, Shivangi, Chaudhary, Mansi, Mitra, Soumitra, Chawla, Bindia, Khursheed, Mohammad Anwar, Saran, Navnoor Kaur, Ramachandran, Rajesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994856/ https://www.ncbi.nlm.nih.gov/pubmed/32004993 http://dx.doi.org/10.1016/j.isci.2019.100817 |
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