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A comparison of the bone and growth phenotype of mdx, mdx:Cmah(−/−) and mdx:Utrn(+/−) murine models with the C57BL/10 wild-type mouse

The muscular dystrophy X-linked (mdx) mouse is commonly used as a mouse model of Duchenne muscular dystrophy (DMD). Its phenotype is, however, mild, and other mouse models have been explored. The mdx:Cmah(−/−) mouse carries a human-like mutation in the Cmah gene and has a severe muscle phenotype, bu...

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Detalles Bibliográficos
Autores principales: Wood, Claire L., Suchacki, Karla J., van ’t Hof, Rob, Cawthorn, Will P., Dillon, Scott, Straub, Volker, Wong, Sze Choong, Ahmed, Syed F., Farquharson, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994935/
https://www.ncbi.nlm.nih.gov/pubmed/31754018
http://dx.doi.org/10.1242/dmm.040659