Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells

The misfolding and aggregation of the largely disordered protein, α-synuclein, is a central pathogenic event that occurs in the synucleinopathies, a group of neurodegenerative disorders that includes Parkinson's disease. While there is a clear link between protein misfolding and neuronal vulner...

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Detalles Bibliográficos
Autores principales: Ugalde, Cathryn L., Annesley, Sarah J., Gordon, Shane E., Mroczek, Katelyn, Perugini, Matthew A., Lawson, Victoria A., Fisher, Paul R., Finkelstein, David I., Hill, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994945/
https://www.ncbi.nlm.nih.gov/pubmed/31848207
http://dx.doi.org/10.1242/dmm.040899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994945/
https://www.ncbi.nlm.nih.gov/pubmed/31848207
http://dx.doi.org/10.1242/dmm.040899

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