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Addressing variability in iPSC-derived models of human disease: guidelines to promote reproducibility

Induced pluripotent stem cell (iPSC) technologies have provided in vitro models of inaccessible human cell types, yielding new insights into disease mechanisms especially for neurological disorders. However, without due consideration, the thousands of new human iPSC lines generated in the past decad...

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Detalles Bibliográficos
Autores principales: Volpato, Viola, Webber, Caleb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994963/
https://www.ncbi.nlm.nih.gov/pubmed/31953356
http://dx.doi.org/10.1242/dmm.042317