LINGO1 is a regulatory subunit of large conductance, Ca(2+)-activated potassium channels

LINGO1 is a transmembrane protein that is up-regulated in the cerebellum of patients with Parkinson’s disease (PD) and Essential Tremor (ET). Patients with additional copies of the LINGO1 gene also present with tremor. Pharmacological or genetic ablation of large conductance Ca(2+)-activated K(+) (B...

Descripción completa

Detalles Bibliográficos
Autores principales: Dudem, Srikanth, Large, Roddy J., Kulkarni, Shruti, McClafferty, Heather, Tikhonova, Irina G., Sergeant, Gerard P., Thornbury, Keith D., Shipston, Michael J., Perrino, Brian A., Hollywood, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994976/
https://www.ncbi.nlm.nih.gov/pubmed/31932443
http://dx.doi.org/10.1073/pnas.1916715117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994976/
https://www.ncbi.nlm.nih.gov/pubmed/31932443
http://dx.doi.org/10.1073/pnas.1916715117

Ejemplares similares