Cargando…

Missing regions within the molecular architecture of human fibrin clots structurally resolved by XL-MS and integrative structural modeling

Upon activation, fibrinogen forms large fibrin biopolymers that coalesce into clots which assist in wound healing. Limited insights into their molecular architecture, due to the sheer size and the insoluble character of fibrin clots, have restricted our ability to develop novel treatments for clotti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klykov, Oleg, van der Zwaan, Carmen, Heck, Albert J. R., Meijer, Alexander B., Scheltema, Richard A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995014/ https://www.ncbi.nlm.nih.gov/pubmed/31924745 http://dx.doi.org/10.1073/pnas.1911785117

Ejemplares similares

Cross-ID: Analysis and Visualization of Complex XL–MS-Driven Protein Interaction Networks
por: de Graaf, Sebastiaan C., et al.
Publicado: (2018)

Circulating Microparticles Alter Formation, Structure, and Properties of Fibrin Clots
por: Zubairova, Laily D., et al.
Publicado: (2015)

Fibrin Clot Structure and Platelet Aggregation in Patients with Aspirin Treatment Failure
por: Neergaard-Petersen, Søs, et al.
Publicado: (2013)

Fibrin γ/γ' influences the secretion of fibrinolytic components and clot structure
por: Cantero, Miriam, et al.
Publicado: (2019)

Thrombin generation and fibrin clot structure after vitamin D supplementation
por: Blondon, Marc, et al.
Publicado: (2019)

S-Nitrosoglutathione Acts as a Small Molecule Modulator of Human Fibrin Clot Architecture
por: Bateman, Ryon M., et al.
Publicado: (2012)

Altered fibrin clot structure and dysregulated fibrinolysis contribute to thrombosis risk in severe COVID-19
por: Wygrecka, Malgorzata, et al.
Publicado: (2022)

Resolving the missing link between single platelet force and clot contractile force
por: Sun, Yueyi, et al.
Publicado: (2021)

Meniscal Repair With Fibrin Clot Augmentation
por: Chahla, Jorge, et al.
Publicado: (2017)

Fibrin Clot Formation and Lysis in Plasma
por: Larsen, Julie Brogaard, et al.
Publicado: (2020)

Glucose Concentration Affects Fibrin Clot Structure and Morphology as Evidenced by Fluorescence Imaging and Molecular Simulations
por: Hood, Jacob E., et al.
Publicado: (2018)

Homocysteine thiolactone contributes to the prognostic value of fibrin clot structure/function in coronary artery disease
por: Sikora, Marta, et al.
Publicado: (2022)

Fibrin Clot Delivery System for Meniscal Repair
por: Jang, Suk Hwan, et al.
Publicado: (2011)

Identification of Fibrin Clot-Bound Plasma Proteins
por: Talens, Simone, et al.
Publicado: (2012)

Patho- physiological role of BDNF in fibrin clotting
por: Amadio, Patrizia, et al.
Publicado: (2019)

Fibrin clot properties and thrombus composition in cirrhosis
por: Driever, Ellen G., et al.
Publicado: (2023)

Multiscale Network Modeling of Fibrin Fibers and Fibrin Clots with Protofibril Binding Mechanics
por: Yesudasan, Sumith, et al.
Publicado: (2020)

Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots
por: Frick, Inga-Maria, et al.
Publicado: (2018)

Cleavage of talin by calpain promotes platelet-mediated fibrin clot contraction
por: Fong, Karen P., et al.
Publicado: (2021)

Fibrin clot structure remains unaffected in young, healthy individuals after transient exposure to diesel exhaust
por: Metassan, Sofian, et al.
Publicado: (2010)

Detection of Citrullinated Fibrin in Plasma Clots of Rheumatoid Arthritis Patients and Its Relation to Altered Structural Clot Properties, Disease-Related Inflammation and Prothrombotic Tendency
por: Bezuidenhout, Johannes A., et al.
Publicado: (2020)

THE CONVERSION OF FIBRINOGEN TO FIBRIN : XIII. DISSOLUTION OF FIBRIN AND INHIBITION OF CLOTTING BY VARIOUS NEUTRAL SALTS
por: Shulman, Sidney, et al.
Publicado: (1953)

Integrating platelet and coagulation activation in fibrin clot formation
por: Swieringa, Frauke, et al.
Publicado: (2018)

Impact of Fibrinogen Carbamylation on Fibrin Clot Formation and Stability
por: Binder, Veronika, et al.
Publicado: (2017)

Fibrin Clot Mistook as a Worm in the Intravenous Line
por: Kim, Jun Hyun, et al.
Publicado: (2020)

Fibrin Clot Formation under Oxidative Stress Conditions
por: Kaufmanova, Jirina, et al.
Publicado: (2021)

A new device for measurement of fibrin clot lysis: application to the Euglobulin Clot Lysis Time
por: Boudjeltia, K Zouaoui, et al.
Publicado: (2002)

Effect of anticoagulants on fibrin clot structure: A comparison between vitamin K antagonists and factor Xa inhibitors
por: Gauer, Julia S., et al.
Publicado: (2020)

Tumour imaging by the detection of fibrin clots in tumour stroma using an anti-fibrin Fab fragment
por: Obonai, Toshifumi, et al.
Publicado: (2016)

The Effect of Synovial Fluid Enzymes on the Biodegradability of Collagen and Fibrin Clots
por: Palmer, Matthew, et al.
Publicado: (2011)

An Antithrombin-Heparin Complex Increases the Anticoagulant Activity of Fibrin Clots
por: Smith, Lesley J., et al.
Publicado: (2008)

Discovery of an uncovered region in fibrin clots and its clinical significance
por: Hisada, Yohei, et al.
Publicado: (2013)

Fibrin Clot Strength in Patients with Diabetes Mellitus Measured by Thrombelastography
por: Maatman, Benjamin T., et al.
Publicado: (2018)

Factor XIII and Fibrin Clot Properties in Acute Venous Thromboembolism
por: Ząbczyk, Michał, et al.
Publicado: (2021)

Fibrin Clot Augmented Repair of Longitudinal Tear of Medial Meniscus
por: Desai, Tarun, et al.
Publicado: (2021)

Reduced fibrin clot lysis in Klinefelter syndrome associated with hypogonadism
por: Chang, Simon, et al.
Publicado: (2022)

Antithrombin Deficiency Is Associated with Prothrombotic Plasma Fibrin Clot Phenotype
por: Natorska, Joanna, et al.
Publicado: (2023)

Finding the missing link: Resolving the Coryneliomycetidae within Eurotiomycetes
por: Wood, A.R., et al.
Publicado: (2015)

Effects of Diabetes Mellitus on Fibrin Clot Structure and Mechanics in a Model of Acute Neutrophil Extracellular Traps (NETs) Formation
por: de Vries, Judith J., et al.
Publicado: (2020)

Synergistic Effect of Bypassing Agents and Sequence Identical Analogue of Emicizumab and Fibrin Clot Structure in the In Vitro Model of Hemophilia A
por: Zong, Yanan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_rusn30df9q8qj5oopk6toajssj