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TrkB hyperactivity contributes to brain dysconnectivity, epileptogenesis, and anxiety in zebrafish model of Tuberous Sclerosis Complex

Tuberous Sclerosis Complex (TSC) is a rare genetic disease that manifests with early symptoms, including cortical malformations, childhood epilepsy, and TSC-associated neuropsychiatric disorders (TANDs). Cortical malformations arise during embryonic development and have been linked to childhood epil...

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Detalles Bibliográficos
Autores principales: Kedra, Magdalena, Banasiak, Katarzyna, Kisielewska, Katarzyna, Wolinska-Niziol, Lidia, Jaworski, Jacek, Zmorzynska, Justyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995026/
https://www.ncbi.nlm.nih.gov/pubmed/31932427
http://dx.doi.org/10.1073/pnas.1910834117