A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo

There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. We previously engineered a lectin, H84T banana lectin (H84T), to retain broad-spectrum activity against multiple influenza strains, including pandemic and...

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Detalles Bibliográficos
Autores principales: Covés-Datson, Evelyn M., King, Steven R., Legendre, Maureen, Gupta, Auroni, Chan, Susana M., Gitlin, Emily, Kulkarni, Vikram V., Pantaleón García, Jezreel, Smee, Donald F., Lipka, Elke, Evans, Scott E., Tarbet, E. Bart, Ono, Akira, Markovitz, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995028/
https://www.ncbi.nlm.nih.gov/pubmed/31932446
http://dx.doi.org/10.1073/pnas.1915152117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995028/
https://www.ncbi.nlm.nih.gov/pubmed/31932446
http://dx.doi.org/10.1073/pnas.1915152117

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