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A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo
There is a strong need for a new broad-spectrum antiinfluenza therapeutic, as vaccination and existing treatments are only moderately effective. We previously engineered a lectin, H84T banana lectin (H84T), to retain broad-spectrum activity against multiple influenza strains, including pandemic and...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995028/ https://www.ncbi.nlm.nih.gov/pubmed/31932446 http://dx.doi.org/10.1073/pnas.1915152117 |