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Simplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations

BACKGROUND: Gene expression profiling has consistently identified three molecular subtypes of lung adenocarcinoma that have prognostic implications. To facilitate stratification of patients with this disease into similar molecular subtypes, we developed and validated a simple, mutually exclusive cla...

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Detalles Bibliográficos
Autores principales: Ruiz-Cordero, Roberto, Ma, Junsheng, Khanna, Abha, Lyons, Genevieve, Rinsurongkawong, Waree, Bassett, Roland, Guo, Ming, Routbort, Mark J., Zhang, Jianjun, Skoulidis, Ferdinandos, Heymach, John, Roarty, Emily B., Tang, Zhenya, Medeiros, L. Jeffrey, Patel, Keyur P., Luthra, Rajyalakshmi, Roy-Chowdhuri, Sinchita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995064/
https://www.ncbi.nlm.nih.gov/pubmed/32005111
http://dx.doi.org/10.1186/s12885-020-6579-z