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Simplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations
BACKGROUND: Gene expression profiling has consistently identified three molecular subtypes of lung adenocarcinoma that have prognostic implications. To facilitate stratification of patients with this disease into similar molecular subtypes, we developed and validated a simple, mutually exclusive cla...
Autores principales: | Ruiz-Cordero, Roberto, Ma, Junsheng, Khanna, Abha, Lyons, Genevieve, Rinsurongkawong, Waree, Bassett, Roland, Guo, Ming, Routbort, Mark J., Zhang, Jianjun, Skoulidis, Ferdinandos, Heymach, John, Roarty, Emily B., Tang, Zhenya, Medeiros, L. Jeffrey, Patel, Keyur P., Luthra, Rajyalakshmi, Roy-Chowdhuri, Sinchita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995064/ https://www.ncbi.nlm.nih.gov/pubmed/32005111 http://dx.doi.org/10.1186/s12885-020-6579-z |
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