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Identification of functional regulatory elements in the human genome using pooled CRISPR screens
BACKGROUND: Genome-scale pooled CRISPR screens are powerful tools for identifying genetic dependencies across varied cellular processes. The vast majority of CRISPR screens reported to date have focused exclusively on the perturbation of protein-coding gene function. However, protein-coding genes co...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995077/ https://www.ncbi.nlm.nih.gov/pubmed/32005150 http://dx.doi.org/10.1186/s12864-020-6497-0 |