MiR-509-3 augments the synthetic lethality of PARPi by regulating HR repair in PDX model of HGSOC

BACKGROUND: PARP inhibitors have been the most promising target drugs with widely proven benefits among ovarian cancer patients. Although platinum-response, HR-related genes, or HRD genomic scar detection are acceptably used in assessment of Olaparib response, there are still evident limitations in...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Chenggong, Cao, Wenyu, Qiu, Chunping, Li, Chengcheng, Dongol, Samina, Zhang, Zhiwei, Dong, Ruifen, Song, Kun, Yang, Xingsheng, Zhang, Qing, Kong, Beihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995078/
https://www.ncbi.nlm.nih.gov/pubmed/32005272
http://dx.doi.org/10.1186/s13045-020-0844-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995078/
https://www.ncbi.nlm.nih.gov/pubmed/32005272
http://dx.doi.org/10.1186/s13045-020-0844-0

Ejemplares similares