Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators

BACKGROUND: Dystrophin deficiency sensitizes skeletal muscle of mice to eccentric contraction (ECC)-induced strength loss. ECC protocols distinguish dystrophin-deficient from healthy, wild type muscle, and test the efficacy of therapeutics for Duchenne muscular dystrophy (DMD). However, given the la...

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Detalles Bibliográficos
Autores principales: Lindsay, Angus, Baumann, Cory W., Rebbeck, Robyn T., Yuen, Samantha L., Southern, William M., Hodges, James S., Cornea, Razvan L., Thomas, David D., Ervasti, James M., Lowe, Dawn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995146/
https://www.ncbi.nlm.nih.gov/pubmed/32007101
http://dx.doi.org/10.1186/s13395-020-0221-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995146/
https://www.ncbi.nlm.nih.gov/pubmed/32007101
http://dx.doi.org/10.1186/s13395-020-0221-2

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