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Mutations of BRCA2 in canine mammary tumors and their targeting potential in clinical therapy

Dogs develop cancer spontaneously with age, with breed-specific risk underlying differences in genetics. Mammary tumors are reported as the most frequent neoplasia in intact female dogs. Their high prevalence in certain breeds suggests a genetic component, as it is the case in human familial breast...

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Detalles Bibliográficos
Autores principales: Thumser-Henner, Pauline, Nytko, Katarzyna J., Rohrer Bley, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995156/
https://www.ncbi.nlm.nih.gov/pubmed/32005245
http://dx.doi.org/10.1186/s12917-020-2247-4