Prevention and management of diarrhea associated with naldemedine among patients receiving opioids: a retrospective cohort study

BACKGROUND: Naldemedine, a novel peripherally-acting mu-opioid receptor antagonist, has improved opioid-induced constipation in randomized controlled trials. The most frequent adverse event of naldemedine is diarrhea, which can cause abdominal pain and often leads to treatment discontinuation. We ai...

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Detalles Bibliográficos
Autores principales: Takagi, Yusuke, Osawa, Gakuji, Kato, Yoriko, Ikezawa, Eri, Kobayashi, Chika, Aruga, Etsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995158/
https://www.ncbi.nlm.nih.gov/pubmed/32005157
http://dx.doi.org/10.1186/s12876-020-1173-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995158/
https://www.ncbi.nlm.nih.gov/pubmed/32005157
http://dx.doi.org/10.1186/s12876-020-1173-z

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