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Prevention and management of diarrhea associated with naldemedine among patients receiving opioids: a retrospective cohort study

BACKGROUND: Naldemedine, a novel peripherally-acting mu-opioid receptor antagonist, has improved opioid-induced constipation in randomized controlled trials. The most frequent adverse event of naldemedine is diarrhea, which can cause abdominal pain and often leads to treatment discontinuation. We ai...

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Detalles Bibliográficos
Autores principales:	Takagi, Yusuke, Osawa, Gakuji, Kato, Yoriko, Ikezawa, Eri, Kobayashi, Chika, Aruga, Etsuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995158/ https://www.ncbi.nlm.nih.gov/pubmed/32005157 http://dx.doi.org/10.1186/s12876-020-1173-z

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