Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease

One of the primary genetic risk factors for Alzheimer’s disease (AD) is the presence of the Ɛ4 allele of apolipoprotein E (APOE). APOE is a polymorphic lipoprotein that is a major cholesterol carrier in the brain. It is also involved in various cellular functions such as neuronal signaling, neuroinf...

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Detalles Bibliográficos
Autores principales: Williams, Tosha, Borchelt, David R., Chakrabarty, Paramita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995170/
https://www.ncbi.nlm.nih.gov/pubmed/32005122
http://dx.doi.org/10.1186/s13024-020-0358-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995170/
https://www.ncbi.nlm.nih.gov/pubmed/32005122
http://dx.doi.org/10.1186/s13024-020-0358-9

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