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Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease
One of the primary genetic risk factors for Alzheimer’s disease (AD) is the presence of the Ɛ4 allele of apolipoprotein E (APOE). APOE is a polymorphic lipoprotein that is a major cholesterol carrier in the brain. It is also involved in various cellular functions such as neuronal signaling, neuroinf...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995170/ https://www.ncbi.nlm.nih.gov/pubmed/32005122 http://dx.doi.org/10.1186/s13024-020-0358-9 |