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A microcarrier-based spheroid 3D invasion assay to monitor dynamic cell movement in extracellular matrix
BACKGROUND: Cell invasion through extracellular matrix (ECM) is a critical step in tumor metastasis. To study cell invasion in vitro, the internal microenvironment can be simulated via the application of 3D models. RESULTS: This study presents a method for 3D invasion examination using microcarrier-...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995242/ https://www.ncbi.nlm.nih.gov/pubmed/32021568 http://dx.doi.org/10.1186/s12575-019-0114-0 |