Cargando…

Development and validation of a reporter cell line for rapid AAV quality control assessment

Adenovirus-associated virus is a powerful vector system for transducing cells in vivo. It is widely used in animal systems due to high transduction efficiency of non-dividing cells with more than a dozen serotypes that have preferential tissue tropism. The viral genome remains episomal in the nucleu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kopera, Huira C., Hilgarth, Roland S., Kopas, Tonya L., Lanigan, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995252/
https://www.ncbi.nlm.nih.gov/pubmed/32021830
http://dx.doi.org/10.1016/j.mex.2020.100800