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Development and validation of a reporter cell line for rapid AAV quality control assessment
Adenovirus-associated virus is a powerful vector system for transducing cells in vivo. It is widely used in animal systems due to high transduction efficiency of non-dividing cells with more than a dozen serotypes that have preferential tissue tropism. The viral genome remains episomal in the nucleu...
Autores principales: | Kopera, Huira C., Hilgarth, Roland S., Kopas, Tonya L., Lanigan, Thomas M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995252/ https://www.ncbi.nlm.nih.gov/pubmed/32021830 http://dx.doi.org/10.1016/j.mex.2020.100800 |
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