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In silico analysis for determining the deleterious nonsynonymous single nucleotide polymorphisms of BRCA genes
Recent advances in DNA sequencing techniques have led to an increase in the identification of single nucleotide polymorphisms (SNPs) in BRCA1 and BRCA2 genes, but no further information regarding the deleterious probability of many of them is available (Variants of Unknown Significance/VUS). As a re...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shiraz University
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995337/ https://www.ncbi.nlm.nih.gov/pubmed/32042831 http://dx.doi.org/10.22099/mbrc.2019.34198.1420 |