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In silico analysis for determining the deleterious nonsynonymous single nucleotide polymorphisms of BRCA genes

Recent advances in DNA sequencing techniques have led to an increase in the identification of single nucleotide polymorphisms (SNPs) in BRCA1 and BRCA2 genes, but no further information regarding the deleterious probability of many of them is available (Variants of Unknown Significance/VUS). As a re...

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Detalles Bibliográficos
Autores principales: Yadegari, Fatemeh, Majidzadeh, Keivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995337/
https://www.ncbi.nlm.nih.gov/pubmed/32042831
http://dx.doi.org/10.22099/mbrc.2019.34198.1420

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