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Lanatoside C Induces G2/M Cell Cycle Arrest and Suppresses Cancer Cell Growth by Attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR Signaling Pathways

Cardiac glycosides (CGs) are a diverse family of naturally derived compounds having a steroid and glycone moiety in their structures. CG molecules inhibit the α-subunit of ubiquitous transmembrane protein Na(+)/K(+)-ATPase and are clinically approved for the treatment of cardiovascular diseases. Rec...

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Detalles Bibliográficos
Autores principales: Reddy, Dhanasekhar, Kumavath, Ranjith, Ghosh, Preetam, Barh, Debmalya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995510/
https://www.ncbi.nlm.nih.gov/pubmed/31783627
http://dx.doi.org/10.3390/biom9120792