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Characterization of the Interaction of Neuropathy Target Esterase with the Endoplasmic Reticulum and Lipid Droplets

Neuropathy target esterase (NTE) is an endoplasmic reticulum (ER)-localized phospholipase that deacylates phosphatidylcholine (PC) and lysophosphatidylcholine (LPC). Loss-of-function mutations in the human NTE gene have been associated with a spectrum of neurodegenerative disorders such as hereditar...

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Detalles Bibliográficos
Autores principales: Chang, Pingan, He, Ling, Wang, Yu, Heier, Christoph, Wu, Yijun, Huang, Feifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995513/
https://www.ncbi.nlm.nih.gov/pubmed/31835418
http://dx.doi.org/10.3390/biom9120848