Induction of Apoptosis and Autophagy in Breast Cancer Cells by a Novel HDAC8 Inhibitor

Epigenetic therapy has been demonstrated to be a viable strategy for breast cancer treatment. In this study, we report the anti-tumor activity of a hydroxamate-based histone deacetylase (HDAC)8-selective inhibitor, HMC, in breast cancer cells. MTT assays showed that HMC inhibited cell viability of M...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiu, Chang-Fang, Chin, Hsien-Kuo, Huang, Wei-Jan, Bai, Li-Yuan, Huang, Hao-Yu, Weng, Jing-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995545/
https://www.ncbi.nlm.nih.gov/pubmed/31817161
http://dx.doi.org/10.3390/biom9120824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995545/
https://www.ncbi.nlm.nih.gov/pubmed/31817161
http://dx.doi.org/10.3390/biom9120824

Ejemplares similares