Biological Evaluation, Molecular Docking, and SAR Studies of Novel 2-(2,4-Dihydroxyphenyl)-1H- Benzimidazole Analogues

In the present study, new 4-(1H-benzimidazol-2-yl)-benzene-1,3-diols, modified in both rings, have been synthesized and their efficacies as acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitors have been determined. The modified Ellman’s spectrophotometric method was applied for t...

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Detalles Bibliográficos
Autores principales: Matysiak, Joanna, Skrzypek, Alicja, Karpińska, Monika, Czarnecka, Kamila, Szymański, Paweł, Bajda, Marek, Niewiadomy, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995558/
https://www.ncbi.nlm.nih.gov/pubmed/31842463
http://dx.doi.org/10.3390/biom9120870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995558/
https://www.ncbi.nlm.nih.gov/pubmed/31842463
http://dx.doi.org/10.3390/biom9120870

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