Molecular Dynamics Simulation of Transmembrane Transport of Chloride Ions in Mutants of Channelrhodopsin

Channelrhodopsins (ChRs) are light-gated transmembrane cation channels which are widely used for optogenetic technology. Replacing glutamate located at the central gate of the ion channel with positively charged amino acid residues will reverse ion selectivity and allow anion conduction. The structu...

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Detalles Bibliográficos
Autores principales: Zhang, Wenying, Yang, Ting, Zhou, Shuangyan, Cheng, Jie, Yuan, Shuai, Lo, Glenn V., Dou, Yusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995576/
https://www.ncbi.nlm.nih.gov/pubmed/31835536
http://dx.doi.org/10.3390/biom9120852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995576/
https://www.ncbi.nlm.nih.gov/pubmed/31835536
http://dx.doi.org/10.3390/biom9120852

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