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Molecular Dynamics Simulation of Transmembrane Transport of Chloride Ions in Mutants of Channelrhodopsin
Channelrhodopsins (ChRs) are light-gated transmembrane cation channels which are widely used for optogenetic technology. Replacing glutamate located at the central gate of the ion channel with positively charged amino acid residues will reverse ion selectivity and allow anion conduction. The structu...
Autores principales: | Zhang, Wenying, Yang, Ting, Zhou, Shuangyan, Cheng, Jie, Yuan, Shuai, Lo, Glenn V., Dou, Yusheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995576/ https://www.ncbi.nlm.nih.gov/pubmed/31835536 http://dx.doi.org/10.3390/biom9120852 |
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